At the Raychaudhuri Lab, we study the basis of immune mediated disease using techniques in human genetics, bioinformatics, and systems biology.
Our group is in the Divisions of Genetics & Rheumatology in the Department of Medicine of the Brigham and Women's Hospital and Harvard Medical School. We are part of the Partners HealthCare Center for Personalized Genetic Medicine, and we are affiliated with the Program in Medical and Population Genetics at the Broad Institute and the Bioinformatics and Integrative Genomics graduate program at and Harvard Medical School.
- Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype
- Fast, sensitive and accurate integration of single-cell data with Harmony
- Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians
- Defining Inflammatory Cell States in Rheumatoid Arthritis Joint Synovial Tissues by Integrating Single-cell Transcriptomics and Mass Cytometry
- IMPACT: Genomic annotation of cell-state-specific regulatory elements inferred from the epigenome of bound transcription factors
- Lymphocyte innateness is defined by underlying transcriptional states reflecting a balance between proliferation and effector functions