At the Raychaudhuri Lab, we study the basis of autoimmune disease using techniques in human genetics, bioinformatics, and systems biology.
Our group is in the Divisions of Genetics & Rheumatology in the Department of Medicine of the Brigham and Women's Hospital and Harvard Medical School. We are part of the Partners HealthCare Center for Personalized Genetic Medicine, and we are affiliated with the Program in Medical and Population Genetics at the Broad Institute and the Bioinformatics and Integrative Genomics graduate program at Harvard.
- Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants
- Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis
- Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci
- A rare coding allele in IFIH1 is protective for psoriatic arthritis
- Investigating methotrexate toxicity within a randomized double-blinded, placebo-controlled trial: Rationale and design of the Cardiovascular Inflammation Reduction Trial-Adverse Events (CIRT-AE) Study
- Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis